diff --git a/.github/workflows/doc.yml b/.github/workflows/doc.yml
index 20ac001..643a6f0 100644
--- a/.github/workflows/doc.yml
+++ b/.github/workflows/doc.yml
@@ -29,21 +29,17 @@ jobs:
       with:
         python-version: ${{ matrix.python-version }}
 
-    - name: Ubuntu - install libsndfile1
-      run: |
-        sudo apt-get update
-        sudo apt-get install --no-install-recommends --yes libsndfile1
+    - name: Install uv
+      uses: astral-sh/setup-uv@v5
 
-    - name: Install package
+    - name: Ubuntu - install libsndfile1 and portaudio
       run: |
-        python -m pip install --upgrade pip
-        pip install -r requirements.txt
+        sudo apt-get update
+        sudo apt-get install --no-install-recommends --yes libsndfile1 portaudio19-dev
 
-    - name: Install docs requirements
-      run: pip install -r docs/requirements.txt
 
     - name: Test building documentation
-      run: python -m sphinx docs/ docs/_build/ -b html -W
+      run: uv run python -m sphinx docs/ docs/_build/ -b html -W
 
     - name: Check links in documentation
-      run: python -m sphinx docs/ docs/_build/ -b linkcheck -W
+      run: uv run python -m sphinx docs/ docs/_build/ -b linkcheck -W
diff --git a/.github/workflows/linter.yml b/.github/workflows/linter.yml
index 9fa4a65..b2db86f 100644
--- a/.github/workflows/linter.yml
+++ b/.github/workflows/linter.yml
@@ -19,11 +19,11 @@ jobs:
       with:
         python-version: '3.10'
 
+    - name: Install uv
+      uses: astral-sh/setup-uv@v5
+
     - name: Install pre-commit hooks
-      run: |
-        pip install pre-commit
-        pre-commit install --install-hooks
+      run: uvx pre-commit install --install-hooks
 
     - name: Code style check via pre-commit
-      run: |
-        pre-commit run --all-files
+      run: uvx pre-commit run --all-files
diff --git a/.github/workflows/publish.yml b/.github/workflows/publish.yml
index 924992c..80c6fe8 100644
--- a/.github/workflows/publish.yml
+++ b/.github/workflows/publish.yml
@@ -25,14 +25,13 @@ jobs:
       with:
         python-version: '3.10'
 
-    - name: Install dependencies
-      run: |
-        python -m pip install --upgrade pip
-        pip install build virtualenv
+    - name: Install uv
+      uses: astral-sh/setup-uv@v5
+
 
     # PyPI package
     - name: Build Python package
-      run: python -m build
+      run: uv build
 
     - name: Publish Python package to PyPI
       uses: pypa/gh-action-pypi-publish@release/v1
@@ -42,12 +41,9 @@ jobs:
       run: |
         sudo apt-get update
         sudo apt-get install --no-install-recommends --yes libsndfile1 sox
-        pip install -r requirements.txt
-        pip install -r docs/requirements.txt
 
     - name: Build documentation
-      run: |
-        python -m sphinx docs/ docs/_build/ -b html
+      run: uv run python -m sphinx docs/ docs/_build/ -b html
 
     - name: Deploy documentation to Github pages
       uses: peaceiris/actions-gh-pages@v4
diff --git a/.github/workflows/test.yml b/.github/workflows/test.yml
index 0975f52..23a0ef5 100644
--- a/.github/workflows/test.yml
+++ b/.github/workflows/test.yml
@@ -29,6 +29,9 @@ jobs:
       with:
         python-version: ${{ matrix.python-version }}
 
+    - name: Install uv
+      uses: astral-sh/setup-uv@v5
+
     - name: Prepare Macos
       run: |
         brew install portaudio
@@ -40,16 +43,11 @@ jobs:
         sudo apt-get install --no-install-recommends --yes libsndfile1 sox portaudio19-dev
       if: matrix.os == 'ubuntu-latest'
 
-    - name: Install dependencies
-      run: |
-        python -V
-        python -m pip install --upgrade pip
-        pip install -r requirements.txt
-        pip install -r tests/requirements.txt
+    - name: Sync Python environment
+      run: uv sync
 
     - name: Test with pytest
-      run: |
-        python -m pytest
+      run: uv run pytest
 
     - name: Upload coverage to Codecov
       uses: codecov/codecov-action@v4
diff --git a/.gitignore b/.gitignore
index 755bd97..f63c7f3 100644
--- a/.gitignore
+++ b/.gitignore
@@ -8,3 +8,4 @@ venv/
 .coverage
 coverage.xml
 docs/api/
+uv.lock
diff --git a/CONTRIBUTING.rst b/CONTRIBUTING.rst
index 897a49c..2fa99e9 100644
--- a/CONTRIBUTING.rst
+++ b/CONTRIBUTING.rst
@@ -22,11 +22,7 @@ you should get the newest development version from Github_::
 
    git clone https://github.com/audeering/audinterface/
    cd audinterface
-   # Create virtual environment for this project
-   # e.g.
-   # virtualenv --python="python3"  $HOME/.envs/audinterface
-   # source $HOME/.envs/audinterface/bin/activate
-   pip install -r requirements.txt
+   uv sync
 
 
 This way,
@@ -50,9 +46,8 @@ are defined in :file:`pyproject.toml`.
 The checks are executed in the CI using `pre-commit`_.
 You can enable those checks locally by executing::
 
-    pip install pre-commit  # consider system wide installation
-    pre-commit install
-    pre-commit run --all-files
+    uvx pre-commit install
+    uvx pre-commit run --all-files
 
 Afterwards ruff_ and codespell_ are executed
 every time you create a commit.
@@ -60,15 +55,14 @@ every time you create a commit.
 You can also install ruff_ and codespell_
 and call it directly::
 
-    pip install ruff codespell  # consider system wide installation
-    ruff check --fix .  # lint all Python files, and fix any fixable errors
-    ruff format .  # format code of all Python files
-    codespell
+    uvx ruff check --fix .  # lint all Python files, and fix any fixable errors
+    uvx ruff format .  # format code of all Python files
+    uvx codespell
 
 It can be restricted to specific folders::
 
-    ruff check audformat/ tests/
-    codespell audformat/ tests/
+    uvx ruff check audinterface/ tests/
+    uvx codespell audinterface/ tests/
 
 
 .. _codespell: https://github.com/codespell-project/codespell/
@@ -81,21 +75,16 @@ Building the Documentation
 --------------------------
 
 If you make changes to the documentation,
-you can re-create the HTML pages using Sphinx_.
-You can install it and a few other necessary packages with::
+you can re-create the HTML pages using Sphinx_::
 
-   pip install -r docs/requirements.txt
-
-To create the HTML pages, use::
-
-   python -m sphinx docs/ build/sphinx/html -b html
+   uv run python -m sphinx docs/ build/html -b html
 
 The generated files will be available
-in the directory :file:`build/sphinx/html/`.
+in the directory :file:`build/html/`.
 
 It is also possible to automatically check if all links are still valid::
 
-   python -m sphinx docs/ build/sphinx/html -b linkcheck
+   uv run python -m sphinx docs/ build/html -b linkcheck
 
 .. _Sphinx: http://sphinx-doc.org
 
@@ -103,14 +92,9 @@ It is also possible to automatically check if all links are still valid::
 Running the Tests
 -----------------
 
-You'll need pytest_ for that.
-It can be installed with::
-
-   pip install -r tests/requirements.txt
-
-To execute the tests, simply run::
+You can run tests with pytest_::
 
-   python -m pytest
+   uv run pytest
 
 .. _pytest: https://pytest.org
 
diff --git a/docs/installation.rst b/docs/installation.rst
index b5726a3..7bcce1f 100644
--- a/docs/installation.rst
+++ b/docs/installation.rst
@@ -5,7 +5,10 @@ To install :mod:`audinterface` run:
 
 .. code-block:: bash
 
-    $ # Create and activate Python virtual environment, e.g.
-    $ # virtualenv --no-download --python=python3 ${HOME}/.envs/audinterface
-    $ # source ${HOME}/.envs/audinterface/bin/activate
     $ pip install audinterface
+
+To interactively test it run:
+
+.. code-block:: bash
+
+    $ uvx --with audinterface ipython
diff --git a/docs/requirements.txt b/docs/requirements.txt
deleted file mode 100644
index 99e5790..0000000
--- a/docs/requirements.txt
+++ /dev/null
@@ -1,8 +0,0 @@
-audb >=1.11.0
-audeer
-sphinx
-sphinx-apipages >=0.1.2
-sphinx-audeering-theme >=1.2.1
-sphinx-autodoc-typehints
-sphinx-copybutton
-toml
diff --git a/pyproject.toml b/pyproject.toml
index 2ea7cd4..5567da1 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -48,6 +48,30 @@ repository = 'https://github.com/audeering/audinterface/'
 documentation = 'https://audeering.github.io/audinterface/'
 
 
+# ===== Dependency groups =================================================
+[dependency-groups]
+dev = [
+    'audb >=1.11.0',
+    'audeer >=1.21.0',
+    'auditok >=0.3.0',
+    'audobject >=0.7.5',
+    'faster-whisper',  # for usage example with ASR
+    'librosa >=0.11.0',
+    'onnxruntime ==1.19.2 ; python_version == "3.9"',
+    'onnxruntime ; python_version >= "3.10"',
+    'pytest',
+    'pytest-cov',
+    'soxr >=0.4.0b1',  # for numpy 2
+    'sphinx',
+    'sphinx-apipages >=0.1.2',
+    'sphinx-audeering-theme >=1.2.1',
+    'sphinx-autodoc-typehints',
+    'sphinx-copybutton',
+    'sybil',
+    'toml',
+]
+
+
 # ===== BUILD-SYSTEM ======================================================
 #
 # Requirements for building the Python package
diff --git a/requirements.txt b/requirements.txt
deleted file mode 100644
index d6e1198..0000000
--- a/requirements.txt
+++ /dev/null
@@ -1 +0,0 @@
--e .
diff --git a/tests/requirements.txt b/tests/requirements.txt
deleted file mode 100644
index c447782..0000000
--- a/tests/requirements.txt
+++ /dev/null
@@ -1,10 +0,0 @@
-audeer >=1.21.0
-audb >=1.11.0
-auditok >=0.3.0
-audobject >=0.7.5
-faster-whisper  # for usage example with ASR
-librosa >=0.11.0
-pytest
-pytest-cov
-soxr >=0.4.0b1  # for numpy 2, https://github.com/dofuuz/python-soxr/issues/28
-sybil